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α-GalCer
Loading...Anti-α-GalCer Products
- PE-CD1d/α-GalCer MHC Tetramer (MHC-LC659)
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- Class: Class I
- Antigen: α-GalCer
- Conjugate: PE
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- APC-CD1d/α-GalCer MHC Tetramer (MHC-LC660)
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- Class: Class I
- Antigen: α-GalCer
- Conjugate: APC
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For Research Use Only. Not For Clinical Use.
alpha-Galactosylceramide (α-GalCer, KRN7000) is a synthetic glycolipid derived from structure-activity relationship studies of galactosylceramides isolated from the marine sponge Agelas mauritianus. α-GalCer is a strong immunostimulant and shows potent anti-tumour activity in many in vivo models. α-GalCer is a potent activator of iNKT cells, and a model CD1d antigen. The invariant T cell receptor of the iNKT cell is able to bind the CD1d:glycolipid complex leading to iNKT cell in both mice and humans.