+ Filter
Loading...
AβpE
Loading...Anti-AβpE Products
- Mouse Anti-AβpE Recombinant Antibody; scFv Fragment (TAB-0833CLV-S(P)) (TAB-0833CLV-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, IHC, DB
Compare
- Mouse Anti-AβpE Recombinant Antibody; scFv Fragment (TAB-0832CLV-S(P)) (TAB-0832CLV-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, IHC, DB
Compare
- Mouse Anti-AβpE Recombinant Antibody; Fab Fragment (TAB-0833CLV-F(E)) (TAB-0833CLV-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, IHC, DB
Compare
- Mouse Anti-AβpE Recombinant Antibody; Fab Fragment (TAB-0832CLV-F(E)) (TAB-0832CLV-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, IHC, DB
Compare
- Mouse Anti-AβpE Recombinant Antibody (TAB-0833CLV) (TAB-0833CLV)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, DB
Compare
- Mouse Anti-AβpE Recombinant Antibody (TAB-0832CLV) (TAB-0832CLV)
-
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, IHC, DB
Compare
View More Products
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
Among the family of Aβ peptides, pyroglutamate-modified Aβ (AβpE) peptides are particularly associated with cytotoxicity in Alzheimer's disease (AD). They represent the dominant fraction of Aβ oligomers in the brains of AD patients, but their accumulation in the brains of elderly individuals with normal cognition is significantly lower. Accumulation of AβpE plaques precedes the formation of plaques of full-length Aβ (Aβ1-40/42). Most of these properties appear to be associated with the higher hydrophobicity of AβpE as well as an increased resistance to enzymatic degradati