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ACTR3

Anti-ACTR3 Products
- Rabbit Anti-ACTR3 Recombinant Antibody (clone JB33-44) (MRO-0122-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: ELISA, WB
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-F, IHC-P, ICC, IF
- AbPlus™ Anti-ACTR3 Magnetic Beads (VS-0724-YC465) (VS-0724-YC465)
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- Target: ACTR3
- Target Species: Human
- Application: IP, Protein Purification
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IF, WB
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, IHC-P
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- Derivation: Mouse
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: WB, IHC, FCM
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- Derivation: Mouse
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: WB, IHC, ICC
- Anti-ACTR3 Immunohistochemistry Kit (VS-0525-XY130)
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- Species Reactivity: Human
- Target: ACTR3
- Application: IHC
- Anti-Mouse ACTR3 Immunohistochemistry Kit (VS-0525-XY131)
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- Species Reactivity: Human, Mouse, Rat
- Target: ACTR3
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the Arp2/3 complex composed of ACTR2/ARP2, ACTR3/ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC (PubMed:9000076, PubMed:9230079, PubMed:11741539). Interacts with WHDC1 (PubMed:18614018). Interacts weakly with MEFV (PubMed:19109554). Interacts with AVIL (PubMed:29058690).
Molecular function
Actin-binding
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