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ADAMTS13
Loading...Anti-ADAMTS13 ProductsBackground
Anti-ADAMTS13 Products
- AbPlus™ Anti-ADAMTS13 Magnetic Beads (VS-0424-XY5) (VS-0424-XY5)
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- Target: ADAMTS13
- Target Species: Human
- Application: IP, Protein Purification
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- Anti-ADAMTS13 Immunohistochemistry Kit (VS-0525-XY154)
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- Species Reactivity: Human
- Target: ADAMTS13
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.