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AKR7A2

Anti-AKR7A2 Products

Mouse Anti-AKR7A2 Recombinant Antibody (clone CBLS-086) (MOB-0565MZ)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
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Mouse Anti-AKR7A2 Recombinant Antibody (clone C10-D5) (MRO-0042-CN)
- Species Reactivity: Human, Zebrafish
- Type: Mouse IgG1
- Application: WB, IF, IHC
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Rabbit Anti-AKR7A2 Polyclonal Antibody (MRO-1632-CN) (MRO-1632-CN)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF
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Chicken Anti-AKR7A2 Polyclonal IgY (BRD-0030MZ)
- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.

The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Protein class

Enzymes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Proximal tubular cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Homodimer.

Molecular function

Oxidoreductase

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