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AKR7A2
The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal tubular cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer.
Molecular function
Oxidoreductase
More Types Infomation
- Mouse Anti-AKR7A2 Recombinant Antibody (clone C10-D5) (MRO-0042-CN)
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- Species Reactivity: Human, Zebrafish
- Type: Mouse IgG1
- Application: WB, IF, IHC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
- Rabbit Anti-AKR7A2 Polyclonal Antibody (MRO-1632-CN) (MRO-1632-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF
- Chicken Anti-AKR7A2 Polyclonal IgY (BRD-0030MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.