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APOD

This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism.
Protein class

Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Fibroblasts, Leydig cells, Melanocytes, Peritubular cells)

Immune cell specificity

Immune cell enriched (memory B-cell)

Cell line specificity

Group enriched (ASC diff, ASC TERT1)

Interaction

Homodimer. In plasma, also exists as a disulfide-linked heterodimer with APOA2.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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