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APOM

The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene.
Protein class

Plasma proteins

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Group enriched (Proximal tubular cells, Hepatocytes)

Immune cell specificity

Immune cell enhanced (basophil)

Cell line specificity

Cell line enriched (Hep G2)

Interaction

Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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