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Angiotensin II

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Anti-Angiotensin II Products

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For Research Use Only. Not For Clinical Use.


Angiotensin II acts at the Na/H exchanger in the proximal tubules of the kidney to stimulate Na reabsorption and H excretion which is coupled to bicarbonate reabsorption. This ultimately results in an increase in blood volume, pressure, and pH. Hence, ACE inhibitors are major anti-hypertensive drugs.
Angiotensin II is being investigated for treating sepsis, septic shock, diabetes mellitus, and acute renal failure, with research also exploring its role in hypertension, the renin-angiotensin system, and idiopathic membranous nephropathy.
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