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Angiotensin II
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- Recombinant Anti-AII Antibody (MOB-47)
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- Derivation: Mouse
- Type: IgG
- Application: WB, IHC, FuncS
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- Recombinant Human Anti-AII Antibody (MHH-47)
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- Derivation: Human
- Type: IgG
- Application: ELISA, WB, IF, FuncS
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- Mouse Anti-Angiotensin II Recombinant Antibody (clone KAA8) (HPAB-0068-YJ)
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- Species Reactivity: Mammal
- Type: Mouse IgG
- Application: Inhib, RIA, ELISA
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- Mouse Anti-Angiotensin II Recombinant Antibody (clone KAA8); scFv Fragment (HPAB-0068-YJ-S(P))
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- Species Reactivity: Mammal
- Type: Mouse scFv
- Application: Neut, RIA, ELISA
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- Mouse Anti-Angiotensin II Recombinant Antibody (clone KAA8); Fab Fragment (HPAB-0068-YJ-F(E))
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- Species Reactivity: Mammal
- Type: Mouse Fab
- Application: Neut, RIA, ELISA
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- Recombinant Anti-Angiotensin II Antibody Fab Fragment (MOB-65-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: WB, FuncS
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- Recombinant Anti-Angiotensin II Antibody scFv Fragment (MOB-65-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: ELISA, IF, FuncS
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- Recombinant Human Anti-AII Antibody Fab Fragment (MHH-47-F(E))
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- Derivation: Human
- Type: Fab
- Application: ELISA, WB, Neut, FuncS
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- Recombinant Human Anti-AII Antibody scFv Fragment (MHH-47-S(P))
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- Derivation: Human
- Type: scFv
- Application: WB, IF, FuncS
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- Recombinant Anti-AII Antibody Fab Fragment (MOB-47-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: IP, RIA, FuncS
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- Recombinant Anti-AII Antibody scFv Fragment (MOB-47-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: IF, FC, Biosensors, FuncS
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- DrugMonitor™ Anti-Angiotensin II Antibody (VS-1224-YC88) (VS-1224-YC88)
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- Specificity: Angiotensin II
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, PK/PD, ADA control
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For Research Use Only. Not For Clinical Use.
Background
Angiotensin II acts at the Na/H exchanger in the proximal tubules of the kidney to stimulate Na reabsorption and H excretion which is coupled to bicarbonate reabsorption. This ultimately results in an increase in blood volume, pressure, and pH. Hence, ACE inhibitors are major anti-hypertensive drugs.
Angiotensin II is being investigated for treating sepsis, septic shock, diabetes mellitus, and acute renal failure, with research also exploring its role in hypertension, the renin-angiotensin system, and idiopathic membranous nephropathy.