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For Research Use Only. Not For Clinical Use.
Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins
Intracellular
Cell type enhanced (Suprabasal keratinocytes, Basal keratinocytes, Urothelial cells, Basal prostatic cells)
Low immune cell specificity
Low cell line specificity
Homo- and heterodimer. Heterodimer (RING-type zinc finger) with BRCA1. Heterodimer (via ANK repeats and BRCT domains) with CSTF1/CSTF-50. Component of the BRCA1-A complex, at least composed of the BRCA1, BARD1, UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Interacts with UBXN1.
Transferase