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BCAN

This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants.
BCAN
Protein class

Plasma proteins

Predicted location

Secreted

Single cell type specificity

Group enriched (Oligodendrocyte precursor cells, Melanocytes, Astrocytes, Horizontal cells)

Immune cell specificity

Immune cell enriched (basophil)

Cell line specificity

Cell line enhanced (HDLM-2, K-562, U-266/70, U-266/84)

Interaction

Interacts with TNR.

More Types Infomation

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