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BLK

Anti-BLK Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors.
Protein class

Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (B-cells)

Immune cell specificity

Group enriched (memory B-cell, naive B-cell)

Cell line specificity

Cell line enhanced (Daudi, REH, RPMI-8226, U-698, U-87 MG)

Interaction

Interacts with CBL (via SH2 domain). Interacts with CD79A and CD79B (via SH2 domain) (By similarity).

Molecular function

Kinase, Transferase, Tyrosine-protein kinase

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