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BLMH

Anti-BLMH Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008]
Protein class

Cancer-related genes, Enzymes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Homohexamer (PubMed:31875550). Interacts with NUDT12 (via ANK repeats) (PubMed:31875550).

Molecular function

Hydrolase, Protease, Thiol protease

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