AbPlus™ Anti-BLMH Magnetic Beads (VS-0724-YC291) (CAT#: VS-0724-YC291)
The AbPlus Anti-BLMH Magnetic Beads (VS-0724-YC291) is an innovative affinity resin which is bound with anti-BLMH specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of BLMH protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, nuclear bodies & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/39548/460_G10_3_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, nuclear bodies & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/39548/460_G10_3_selected.jpg
Figure 2 High expression in skin 1
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/39548/ihc_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/39548/ihc_selected.jpg
Figure 3 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Cells in tubules Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64307/147148_A_8_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Cells in tubules Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64307/147148_A_8_5.jpg
Figure 4 Testis
(Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64307/147148_A_6_6.jpg
(Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64307/147148_A_6_6.jpg
Figure 5 Skin
(Cells in basal layer Staining: Low Intensity: Moderate Quantity: <25% Cells in corneal layer Staining: High Intensity: Strong Quantity: 75%-25% Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Endothelial cells Staining: Low Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64307/147148_B_7_1.jpg
(Cells in basal layer Staining: Low Intensity: Moderate Quantity: <25% Cells in corneal layer Staining: High Intensity: Strong Quantity: 75%-25% Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Endothelial cells Staining: Low Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64307/147148_B_7_1.jpg
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000108578-BLMH
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000108578-BLMH
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-BLMH specific antibody
- Target
- BLMH
- Immunogen
- Recombinant human BLMH/Bleomycin Hydrolase, aa 2-455.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008]
- Alternative Names
- Bleomycin Hydrolase; BLM Hydrolase; EC 3.4.22.40; BMH; BH;
- Gene ID
- 642
- UniProt ID
- Q13867
Downloads
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IgG Antibody Products
Antibody Magnetic Beads
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2272MZ | Mouse Anti-BLMH Recombinant Antibody (clone 3080D5b) | WB | Mouse IgG2b |
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