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BNIP3L

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Anti-BNIP3L ProductsBackground

Anti-BNIP3L Products

Recombinant Rabbit Anti-BNIP3L Antibody (clone R01-0F5) (VS3-FY164)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-P
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Mouse Anti-BNIP3L Recombinant Antibody (clone 1H10B3) (VS7-HM251)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
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For Research Use Only. Not For Clinical Use.

Background

This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c.

Protein class

Cancer-related genes, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Erythroid cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Self-associates. Interacts with BNIP3 and STEAP3. Interacts (via BH3 domain) with SPATA18 (via coiled-coil domains). (Microbial infection) Interacts with human adenovirus-2 E1B 19 kDa protein.

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