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BoNT/A HN
BoNTs (botulinum neurotoxin serotypes) act preferentially on cholinergic nerve endings to block acetylcholine release. The action of BoNTs involves three steps: (1) binding to receptors on the presynaptic membranes via the C-terminus of the heavy chain HC; (2) translocation of the light chain into the cytosol via the N-terminus of the heavy chain HN; and (3) cleavage of one or more key components in the synaptic vesicle docking and fusion protein complex by the zinc protease activity of the light chain.
- Recombinant Human Anti-BoNT/A HN Antibody Fab Fragment (4A4) (FAMAB-0036-YC-F(E))
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- Derivation: Phage display library
- Species Reactivity: BoNT/A
- Type: Human Fab
- Application: ELISA, Neut
- Recombinant Human Anti-BoNT/A HN Antibody Fab Fragment (3D4) (FAMAB-0035-YC-F(E))
-
- Derivation: Phage display library
- Species Reactivity: BoNT/A
- Type: Human Fab
- Application: ELISA, Neut
- Recombinant Human Anti-BoNT/A HN Antibody scFv Fragment (4A4) (FAMAB-0036-YC-S(P))
-
- Derivation: Phage display library
- Species Reactivity: BoNT/A
- Type: Human scFv
- Application: ELISA, Neut
- Recombinant Human Anti-BoNT/A HN Antibody scFv Fragment (3D4) (FAMAB-0035-YC-S(P))
-
- Derivation: Phage display library
- Species Reactivity: BoNT/A
- Type: Human scFv
- Application: ELISA, Neut
- Recombinant Human Anti-BoNT/A HN Antibody (4A4) (FAMAB-0036YC)
-
- Derivation: Phage display library
- Species Reactivity: BoNT/A
- Type: Human IgG
- Application: ELISA, Neut
- Recombinant Human Anti-BoNT/A HN Antibody (3D4) (FAMAB-0035YC)
-
- Derivation: Phage display library
- Species Reactivity: BoNT/A
- Type: Human IgG
- Application: ELISA, Neut
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For Research Use Only. Not For Clinical Use.