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CCT6B
Anti-CCT6B Recombinant Antibody Products
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB
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For Research Use Only. Not For Clinical Use.
This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Predicted location
Intracellular
Single cell type specificity
Group enriched (Spermatocytes, Early spermatids, Late spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (RPMI-8226)
Interaction
Component of the chaperonin-containing T-complex (TRiC), a heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
Molecular function
Chaperone
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