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CD51

Anti-CD51 Products

Mouse Anti-CD51 Recombinant Antibody (clone 3H1A5) (VS7-HM613)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FCM
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For Research Use Only. Not For Clinical Use.

Background

The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions