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CDC20
Anti-CDC20 Recombinant Antibody Products
- Anti-CDC20 Immunohistochemistry Kit (VS-0325-XY379)
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- Species Reactivity: Human
- Target: CDC20
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Protein class
Cancer-related genes, Plasma proteins, Transporters
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Extravillous trophoblasts, Early spermatids, Spermatocytes, Erythroid cells, Cytotrophoblasts)
Immune cell specificity
Group enriched (T-reg, NK-cell, memory B-cell, memory CD8 T-cell, memory CD4 T-cell)
Cell line specificity
Low cell line specificity
Interaction
Component of a complex with CDC20, CDC27, SPATC1 and TUBG1 (By similarity). Interacts with NEUROD2 (By similarity). Interacts with dimeric MAD2L1 in its closed conformation form (PubMed:9811605, PubMed:9637688, PubMed:15525512, PubMed:19098431, PubMed:29162720). Interacts with BUB1B (PubMed:15525512, PubMed:18997788, PubMed:19098431). The phosphorylated form interacts with APC/C (PubMed:9811605, PubMed:9734353, PubMed:9637688). Interacts with NINL (PubMed:17403670). May interact with MAD2L2 (PubMed:11459826). Interacts with CDK5RAP2 (PubMed:19282672). Interacts with SIRT2 (PubMed:22014574). Interacts with isoform 1 of NEK2 (PubMed:20034488). Interacts with HSF1 (via phosphorylated form); this interaction occurs in mitosis in a MAD2L1-dependent manner and prevents PLK1-stimulated degradation of HSF1 by blocking the recruitment of the SCF(BTRC) ubiquitin ligase complex (PubMed:18794143). Interacts (via the N-terminal substrate-binding domain) with FBXO5 (By similarity). Interacts with CCNF (PubMed:27653696).
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