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CDC20

Anti-CDC20 Products

Recombinant Mouse Anti-Human CDC20 Antibody (clone CB9) (MOB-2466MZ)
- Species Reactivity: Xenopus
- Type: Mouse antibody
- Application: ELISA, FC, WB
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Anti-CDC20 Immunohistochemistry Kit (VS-0325-XY379)
- Species Reactivity: Human
- Target: CDC20
- Application: IHC
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Anti-Human CDC20 Immunohistochemistry Kit (VS-0525-XY1256)
- Species Reactivity: Human
- Target: CDC20
- Application: IHC
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For Research Use Only. Not For Clinical Use.

Background

Protein class

Cancer-related genes, Plasma proteins, Transporters

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Extravillous trophoblasts, Early spermatids, Spermatocytes, Erythroid cells, Cytotrophoblasts)

Immune cell specificity

Group enriched (T-reg, NK-cell, memory B-cell, memory CD8 T-cell, memory CD4 T-cell)

Cell line specificity

Low cell line specificity

Interaction

Component of a complex with CDC20, CDC27, SPATC1 and TUBG1 (By similarity). Interacts with NEUROD2 (By similarity). Interacts with dimeric MAD2L1 in its closed conformation form (PubMed:9811605, PubMed:9637688, PubMed:15525512, PubMed:19098431, PubMed:29162720). Interacts with BUB1B (PubMed:15525512, PubMed:18997788, PubMed:19098431). The phosphorylated form interacts with APC/C (PubMed:9811605, PubMed:9734353, PubMed:9637688). Interacts with NINL (PubMed:17403670). May interact with MAD2L2 (PubMed:11459826). Interacts with CDK5RAP2 (PubMed:19282672). Interacts with SIRT2 (PubMed:22014574). Interacts with isoform 1 of NEK2 (PubMed:20034488). Interacts with HSF1 (via phosphorylated form); this interaction occurs in mitosis in a MAD2L1-dependent manner and prevents PLK1-stimulated degradation of HSF1 by blocking the recruitment of the SCF(BTRC) ubiquitin ligase complex (PubMed:18794143). Interacts (via the N-terminal substrate-binding domain) with FBXO5 (By similarity). Interacts with CCNF (PubMed:27653696).

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