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CDC40
Loading...Anti-CDC40 Products
- Rabbit Anti-CDC40 Recombinant Antibody (clone CBACN-130) (MRO-0329-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Anti-Mouse CDC40 Immunohistochemistry Kit (VS-0525-XY1264)
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- Species Reactivity: Human, Mouse, Rat
- Target: CDC40
- Application: IHC
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- Anti-CDC40 Immunohistochemistry Kit (VS-0525-XY1263)
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- Species Reactivity: Human
- Target: CDC40
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Early spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the pre-catalytic and catalytic spliceosome complexes (PubMed:11991638, PubMed:28502770, PubMed:28076346, PubMed:29361316, PubMed:29360106, PubMed:29301961). Component of the postcatalytic spliceosome P complex (PubMed:30705154). Interacts with PPIL1; this interaction leads to CDC40 isomerization (PubMed:33220177).
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