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CDH13
Loading...Anti-CDH13 Products
- PE-A*24:02/Human CDH13 (SYLDSGIHF) MHC Tetramer (MHC-LC3296)
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- Class: Class I
- Antigen: CDH13
- Antigen Species: Human
- Peptide: SYLDSGIHF
- Conjugate: PE
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- Rabbit Anti-CDH13 Recombinant Antibody (clone JB14-48) (MRO-0707-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: IHC, WB
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- AbPlus™ Anti-Cdh13 Magnetic Beads (VS-0724-YC607) (VS-0724-YC607)
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- Target: Cdh13
- Target Species: Mouse
- Application: IP, Protein Purification
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- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, IHC-P
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- Anti-CDH13 Immunohistochemistry Kit (VS-0525-XY1284)
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- Species Reactivity: Human
- Target: CDH13
- Application: IHC
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- Anti-Mouse CDH13 Immunohistochemistry Kit (VS-0525-XY1285)
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- Species Reactivity: Human, Mouse, Rat
- Target: CDH13
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. This gene is highly expressed in the vasculature including endothelial cells, smooth muscle cells and pericytes, where the encoded protein binds to adiponectin and has been implicated in the modulation of angiogenesis.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Group enriched (Inhibitory neurons, Oligodendrocyte precursor cells, Excitatory neurons)
Immune cell specificity
Immune cell enhanced (non-classical monocyte)
Cell line specificity
Cell line enhanced (LHCN-M2, U-138 MG, U-87 MG)
Interaction
By contrast to classical cadherins, homodimerization in trans is not mediated by cadherin EC1 domain strand-swapping, but instead through a homophilic adhesive interface which joins two elongated EC1-EC2 domains through a region near their Ca2+-binding sites to form a tetrahedral, X-like shape.
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