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CHD6
Anti-CHD6 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013]
Protein class
Disease related genes, Enzymes, Plasma proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with NFE2L2; involved in activation of the transcription. (Microbial infection) Interacts with the influenza A polymerase complex composed fo PB1, PB2 and PA. (Microbial infection) Interacts (via N-terminus) with human papillomavirus protein E8^E2C (via C-terminus); this interaction induces transcriptional repression of the viral genome.
Molecular function
Chromatin regulator, DNA-binding, Helicase, Hydrolase
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