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CLC

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. [provided by RefSeq, Jul 2008]
Protein class

Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Erythroid cells)

Immune cell specificity

Group enriched (basophil, eosinophil)

Cell line specificity

Cell line enriched (HMC-1)

Interaction

Interacts with CEL.

More Types Infomation

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