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CLECL1

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For Research Use Only. Not For Clinical Use.


Background

May function in mediating immune cell-cell interactions. May act as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation. May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immune response.
Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (B-cells, Kupffer cells, Langerhans cells, monocytes, Plasma cells, dendritic cells, Macrophages, Hofbauer cells)

Immune cell specificity

Immune cell enhanced (memory B-cell)

Cell line specificity

Group enriched (HEL, Karpas-707, U-698, U-937)

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