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CMV UL40

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For Research Use Only. Not For Clinical Use.


Plays a role in the protection against host NK-cell cytotoxicity by upregulating the cell surface expression of HLA-E independent of TAP (HLA-E has an inhibitory effect on the cytotoxic activity of the NK cell). Promotes also cell surface expression of UL18, another viral protein involved in NK-cell evasion.
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