CSE1L
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Loading...- Rabbit Anti-CSE1L Recombinant Antibody (clone JU34-33) (MRO-0353-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB
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- Anti-CSE1L Immunohistochemistry Kit (VS-0325-XY558)
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- Species Reactivity: Human, Mouse, Rat
- Target: CSE1L
- Application: IHC
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- Anti-Human CSE1L Immunohistochemistry Kit (VS-0525-XY1702)
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- Species Reactivity: Human
- Target: CSE1L
- Application: IHC
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- Anti-Mouse CSE1L Immunohistochemistry Kit (VS-0525-XY1703)
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- Species Reactivity: Human, Mouse
- Target: CSE1L
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form.
Protein class
Cancer-related genes, Plasma proteins, Transporters
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Spermatocytes, Spermatogonia)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Found in a complex with CSE1L/XPO2, Ran and KPNA2 (PubMed:9323134, PubMed:9786944). Binds with high affinity to importin-alpha only in the presence of RanGTP. The complex is dissociated by the combined action of RanBP1 and RanGAP1 (PubMed:9323134). Interacts with CFTR (PubMed:20933420).
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