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CXCL10

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For Research Use Only. Not For Clinical Use.


Background

C-X-C motif chemokine ligand 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is an 8.7 kDa protein that in humans is encoded by the CXCL10 gene. C-X-C motif chemokine 10 is a small cytokine belonging to the CXC chemokine family.
CXCL10
Protein class

Cancer-related genes, Human disease related genes, Plasma proteins

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Basal respiratory cells, Macrophages, Kupffer cells, Glandular and luminal cells, Plasma cells, Langerhans cells)

Immune cell specificity

Group enriched (intermediate monocyte, non-classical monocyte, classical monocyte)

Cell line specificity

Cell line enhanced (BJ hTERT+, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, GAMG, RPMI-8226, RT4, THP-1)

Interaction

Monomer, dimer, and tetramer (PubMed:12737818). Interacts with CXCR3 (via N-terminus) (PubMed:19151743).

Molecular function

Cytokine

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