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DEFB4A
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For Research Use Only. Not For Clinical Use.
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation.
Protein class
Transporters
Predicted location
Secreted
Single cell type specificity
Group enriched (Basal respiratory cells, Pancreatic endocrine cells, Club cells, Exocrine glandular cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (EFO-21)
Molecular function
Antibiotic, Antimicrobial, Defensin
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