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DLX6
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. This family is comprised of at least 6 different members that encode proteins with roles in forebrain and craniofacial development. This gene is in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7.
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Extravillous trophoblasts, Endometrial ciliated cells, Cytotrophoblasts, Glandular and luminal cells, Early spermatids, Syncytiotrophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AN3-CA, BEWO, HAP1, SH-SY5Y, SuSa)
Molecular function
Developmental protein, DNA-binding
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