DYNLRB2

Formats

Anti-DYNLRB2 Recombinant Antibody Products

Mouse Anti-DYNLRB2 Recombinant Antibody (clone 25H6) (MOB-3312z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA, IHC, WB
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For Research Use Only. Not For Clinical Use.

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Early spermatids, Late spermatids, Spermatocytes, Respiratory ciliated cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HDLM-2, MCF7, RPTEC TERT1, SCLC-21H)

Interaction

Homodimer (Probable). The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. Interacts with DYNC1I1 and DYNC1I2. Self-associates. Interacts with DYNLRB1.

Molecular function

Motor protein

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