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EPHA6
EPHA6 (EPH Receptor A6) is a Protein Coding gene. Diseases associated with EPHA6 include Oculoauricular Syndrome. Among its related pathways are Development Slit-Robo signaling and EPH-Ephrin signaling. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is EPHA3.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Inhibitory neurons, Excitatory neurons, Astrocytes, Early spermatids, Late spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HEK93, U-266/70)
Interaction
Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses (By similarity). Interacts (via SAM domain) with ANKS1A (via SAM domain) (By similarity).
Molecular function
Kinase, Receptor, Transferase, Tyrosine-protein kinase
More Types Infomation
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- Species Reactivity: Human
- Application: WB
-
- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
- Rat Anti-Epha6 Recombinant Antibody (clone CBL307) (NEUT-728CQ)
-
- Species Reactivity: Mouse
- Type: Rat IgG1
- Application: Block, WB
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.