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ESAM
Loading...Anti-ESAM Products
- Rabbit Anti-ESAM Recombinant Antibody (clone CBE254) (MOB-269YJL)
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
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- CytoStream™ Rat Anti-ESAM Recombinant Antibody (clone 1G8) (VS-0225-XY109)
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- Species Reactivity: Mouse
- Type: Rat IgG2a, kappa
- Application: FC
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- Anti-Mouse ESAM Immunohistochemistry Kit (VS-0525-XY2364)
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- Species Reactivity: Mouse
- Target: ESAM
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
ESAM is a gene that encodes a cell adhesion molecule that is specifically expressed in endothelial cells. It is involved in the regulation of cell-cell adhesion and the stabilization of endothelial junctions. ESAM is important in maintaining the integrity of the blood-brain barrier and the blood-retinal barrier. It contributes to the regulation of vascular permeability and leukocyte transmigration, which are crucial for inflammation and immune response. ESAM is also involved in angiogenesis, the formation of new blood vessels, and its dysregulation can contribute to various diseases, including cancer and cardiovascular disorders.
Protein class
Plasma proteins
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Adipocytes, Endothelial cells, Sertoli cells, Hepatic stellate cells, Smooth muscle cells)
Immune cell specificity
Immune cell enhanced (basophil, naive B-cell)
Cell line specificity
Group enriched (HEL, HUVEC TERT2, TIME)
Interaction
Interacts with MAGI1.
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