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FBP2
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a gluconeogenesis regulatory enzyme which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate.
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Group enriched (Gastric mucus-secreting cells, Skeletal myocytes, Spermatogonia)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BEWO, CACO-2, HMC-1, MCF7, OE19, PC-3, SiHa)
Interaction
Homotetramer. Interacts with ALDOA; the interaction blocks inhibition by physiological concentrations of AMP and reduces inhibition by Ca(2+). Interacts with alpha-actinin and F-actin.
Molecular function
Allosteric enzyme, Hydrolase
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