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FERMT1
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- Anti-FERMT1 Immunohistochemistry Kit (VS-0325-XY830)
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- Species Reactivity: Human
- Target: FERMT1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the fermitin family, and contains a FERM domain and a pleckstrin homology domain. The encoded protein is involved in integrin signaling and linkage of the actin cytoskeleton to the extracellular matrix. Mutations in this gene have been linked to Kindler syndrome.
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Pancreatic endocrine cells, Oligodendrocyte precursor cells, Basal squamous epithelial cells, Undifferentiated cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (CAPAN-2, HaCaT, HBEC3-KT, OE19, RT4)
Interaction
Interacts with the cytoplasmic domain of integrins ITGB1 and ITGB3.
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