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GAK

Anti-GAK Products
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- Species Reactivity: Human
- Application: WB
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- Species Reactivity: Human
- Type: Camelid VHH
- Application: ELISA
- Mouse Anti-GAK Recombinant Antibody (VS-0224-XY51) (VS-0224-XY51)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG2a
- Application: ELISA, WB, IF, IP, IHC-P
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- Derivation: Llama
- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA
- Anti-GAK Immunohistochemistry Kit (VS-0325-XY890)
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- Species Reactivity: Human, Mouse, Rat
- Target: GAK
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
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