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GAL

This gene encodes a neuroendocrine peptide that is widely expressed in the central and peripheral nervous systems and also the gastrointestinal tract, pancreas, adrenal gland and urogenital tract. The encoded protein is a precursor that is proteolytically processed to generate two mature peptides: galanin and galanin message-associated peptide (GMAP). Galanin has diverse physiological functions including nociception, feeding and energy homeostasis, osmotic regulation and water balance. GMAP has been demonstrated to possess antifungal activity and hypothesized to be part of the innate immune system.
Protein class

Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Secreted

Single cell type specificity

Group enriched (Prostatic glandular cells, Endometrial ciliated cells, Exocrine glandular cells, Endometrial stromal cells, Extravillous trophoblasts, Pancreatic endocrine cells, Ductal cells, Glandular and luminal cells, Urothelial cells, Basal prostatic cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (CACO-2, HEK93, K-562, NB-4, SH-SY5Y)

Molecular function

Hormone, Neuropeptide

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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