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GATA5
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.
Protein class
Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Gastric mucus-secreting cells, Intestinal goblet cells, Hepatic stellate cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (EFO-21, HEL, K-562, SiHa, T-47d)
Molecular function
Activator, DNA-binding
More Types Infomation