+ Filter
Loading...
GRAP2
Anti-GRAP2 Recombinant Antibody Products
CompareMore Infomation
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (granulocytes, Macrophages, NK-cells, T-cells, Erythroid cells)
Immune cell specificity
Group enriched (naive CD8 T-cell, memory CD8 T-cell, gdT-cell, MAIT T-cell, memory CD4 T-cell, T-reg, naive CD4 T-cell)
Cell line specificity
Group enriched (HEL, JURKAT, K-562, MOLT-4)
Interaction
Interacts with phosphorylated LIME1 upon TCR activation (By similarity). Interacts with phosphorylated LAT and LAX1 upon TCR activation. Interacts with SHB. Interacts with PTPN23.
More Types Infomation