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HAP1

Anti-HAP1 Products

Recombinant Mouse Anti-Rat HAP1 Antibody (clone 2C7) (MOB-1823MZ)
- Species Reactivity: Rat
- Type: Mouse antibody
- Application: ICC/IF, IHC-P, IHC-Fr, IP, WB
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Anti-HAP1 Immunohistochemistry Kit (VS-0325-XY992)
- Species Reactivity: Human, Mouse, Rat
- Target: HAP1
- Application: IHC
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More Infomation

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For Research Use Only. Not For Clinical Use.

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Glandular and luminal cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (REH)

Interaction

Self-associates. Interacts with HTT/huntingtin; enhanced by an expanded polyglutamine repeat within HTT. Interacts with DCTN1; decreased in presence of HTT with expanded polyglutamine repeat. Interacts with KLC2. Interacts with ITPR1 and APP. Interacts with AR; decreased by an expanded polyglutamine repeat within AR. Interacts with YWHAZ. Interacts with BDNF and SORT1; probably forming a complex involved in proBDNF trafficking, degradation and processing. Interacts with TBP, AHI1, HGS and KALRN. Interacts with KIF5A, KIF5B, KIF5C and GABRB3; indicative for an HAP1:KIF5 complex transporting a GABA(A) receptor as cargo. Interacts with ATXN3; in STBs with ATXN3 poly-Gln region with 27 repeats (normal population) and 79 repeats (spinocerebellar ataxia 3 (SCA3) patients) associating in the same strength. Interacts with NTRK2; HAP1 stabilizes association of NTRK2 with SORT1 preventing NTRK2 degradation. Interacts with CCDC113.

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