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HIV-1 Protease
Loading...Anti-HIV-1 Protease Products
- Recombinant Anti-HIV-1 Protease Antibody (MOB-490)
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- Derivation: Mouse
- Species Reactivity: HIV
- Type: IgG
- Application: ELISA, IP, FuncS
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- Recombinant Human Anti-HIV-1 Protease Antibody Fab Fragment (MHH-490-F(E))
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- Derivation: Human
- Species Reactivity: HIV
- Type: Fab
- Application: IF, ELISA, FuncS
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- Recombinant Human Anti-HIV-1 Protease Antibody scFv Fragment (MHH-490-S(P))
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- Derivation: Human
- Species Reactivity: HIV
- Type: scFv
- Application: FC, ELISA, FuncS
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- Recombinant Anti-HIV-1 Protease Antibody Fab Fragment (MOB-490-F(E))
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- Derivation: Mouse
- Species Reactivity: HIV
- Type: Fab
- Application: WB, ELISA, FuncS
Compare
- Recombinant Anti-HIV-1 Protease Antibody scFv Fragment (MOB-490-S(P))
-
- Derivation: Mouse
- Species Reactivity: HIV
- Type: scFv
- Application: Neut, WB, FuncS
Compare
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For Research Use Only. Not For Clinical Use.
Background
HIV-1 protease is a retroviral aspartyl protease (retropepsin) that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV protease cleaves newly synthesized polyproteins at the appropriate places to create the mature protein components of an infectious HIV virion. Without effective HIV protease, HIV virions remain uninfectious. Thus, mutation of HIV protease's active site or inhibition of its activity disrupts HIV's ability to replicate and infect additional cells, making HIV protease inhibition the subject of considerable pharmaceutical research.