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HOMER1
Loading...Anti-HOMER1 Products
- Rabbit Anti-HOMER1 Recombinant Antibody (VS-0223-WK37) (VS-0223-WK37)
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- Derivation: Rabbit
- Species Reactivity: Rat, Mouse, Human
- Type: Rabbit IgG
- Application: WB, IP, ICC
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- Guinea pig Anti-HOMER1 Recombinant Antibody (VS-0223-WK38) (VS-0223-WK38)
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- Derivation: Guinea pig
- Species Reactivity: Rat, Mouse, Human
- Type: Guinea pig IgG
- Application: WB, ICC
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- AbPlus™ Anti-HOMER1 Magnetic Beads (VS-0724-YC988) (VS-0724-YC988)
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- Target: HOMER1
- Target Species: Human
- Application: IP, Protein Purification
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- Anti-HOMER1 Immunohistochemistry Kit (VS-0525-XY3247)
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- Species Reactivity: Human
- Target: HOMER1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. [provided by RefSeq, Jul 2008]
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Excitatory neurons, Inhibitory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Low cell line specificity
Interaction
Tetramer; this tetrameric structure is critical for forming the high-order complex with SHANK1, which in turn is necessary for the structural and functional integrity of dendritic spines (By similarity). Interacts with GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2 and SHANK3 (PubMed:10464340). Interacts with IFT57 and OPHN1 (By similarity). Isoform 1 encodes a coiled-coil structure that mediates homo- and heteromultimerization (By similarity). Interacts with SHANK1; forms high-order polymerized complex with a mesh-like network structure, at least composed of SHANK1, HOMER1 and DLGAP1; the complex formation is SHANK1 multimerization dependent (By similarity).Interacts with SHANK1; forms high-order polymerized complex with a mesh-like network structure, at least composed of SHANK1, HOMER1 and DLGAP1; the complex formation is SHANK1 multimerization dependent (By similarity). Interacts with NFATC4 (PubMed:18218901). Interacts with DAGLA (via PPXXF motif); this interaction is required for the cell membrane localization of DAGLA (By similarity). Interacts with SRGAP2 (By similarity).
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