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HTATSF1
Loading...Anti-HTATSF1 Products
- AbPlus™ Anti-HTATSF1 Magnetic Beads (VS-0724-YC687) (VS-0724-YC687)
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- Target: HTATSF1
- Target Species: Human
- Application: IP, Protein Purification
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- Anti-HTATSF1 Immunohistochemistry Kit (VS-0325-XY1079)
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- Species Reactivity: Human, Mouse, Rat
- Target: HTATSF1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cardiomyocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of a complex which is at least composed of HTATSF1/Tat-SF1, the P-TEFb complex components CDK9 and CCNT1, RNA polymerase II, SUPT5H, and NCL/nucleolin. Interacts with GTF2F2/RAP30 and POLR2A. Interacts with TCERG1/CA150. Interacts with SF3A2/SAP62 and the spliceosomal U small nuclear ribonucleoproteins (snRNPs).
Molecular function
Activator, RNA-binding
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