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HTR3B
Anti-HTR3B Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, ELISA, FC, ICC
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- Mouse Anti-HTR3B Recombinant Antibody (clone 2H9H5) (VS7-0425-WR103)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, ICC, FC
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- Mouse Anti-HTR3B Recombinant Antibody (clone 4G6H7) (VS7-0425-WR104)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
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For Research Use Only. Not For Clinical Use.
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011]
Protein class
FDA approved drug targets
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Excitatory neurons, Oligodendrocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Not detected
Interaction
Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex.
Molecular function
Ion channel, Ligand-gated ion channel, Receptor
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