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HTR3B
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Protein class
FDA approved drug targets
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Excitatory neurons, Oligodendrocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Not detected
Interaction
Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex.
Molecular function
Ion channel, Ligand-gated ion channel, Receptor
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, ELISA, FC, ICC
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For Research Use Only. Not For Clinical Use.