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IGFBP6

Anti-IGFBP6 ProductsBackground
Anti-IGFBP6 Products
- Chicken Anti-IGFBP6 Polyclonal IgY (BRD-0273MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
IGFBP6 (Insulin Like Growth Factor Binding Protein 6) is a Protein Coding gene. Diseases associated with IGFBP6 include Insulin-Like Growth Factor I and Exfoliative Ichthyosis. Among its related pathways are Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include insulin-like growth factor binding and insulin-like growth factor II binding. An important paralog of this gene is IGFBP5.
Protein class
Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Group enriched (Peritubular cells, Fibroblasts, Sertoli cells, Leydig cells, Basal respiratory cells, Smooth muscle cells)
Immune cell specificity
Immune cell enhanced (eosinophil, non-classical monocyte)
Cell line specificity
Cell line enhanced (ASC TERT1, BJ, BJ hTERT+, fHDF/TERT166, hTERT-RPE1, U-87 MG)
Interaction
Interacts (via C-terminal domain) with PHB2.
Molecular function
Growth factor binding
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