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IHH

Anti-IHH Products
- Mouse Anti-IHH Recombinant Antibody (clone 36C7) (MOB-3454z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, IHC, FC
- Rat Anti-IHH Recombinant Antibody (clone CBL664) (NEUT-1161CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2b
- Application: Neut
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG3
- Application: WB
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IHC-P
- Anti-IHH Immunohistochemistry Kit (VS-0325-XY1112)
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- Species Reactivity: Human
- Target: IHH
- Application: IHC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IP, IHC-P
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Nov 2015]
Protein class
Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Granulosa cells, Enteroendocrine cells, Intestinal goblet cells, Distal enterocytes, Undifferentiated cells, Proximal enterocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (CACO-2, OE19)
Interaction
Homooligomer (indian hedgehog protein N-product). Interacts with BOC and CDON. Interacts with PTCH1. Interacts with glypican GPC3 (By similarity).
Molecular function
Developmental protein, Hydrolase, Protease
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