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Anti-IL15R Recombinant Antibody Products

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Anti-IL15R ProductsIL15RFeatured ProductsCreative Quality ControlCustomer ReviewsrAb ProductionrAb ModalitiesIL15R-Targeted Drug Information

Anti-IL15R Products

    • Species Reactivity: Human
    • Application: Cytotoxicity assay, Function study
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    • Species Reactivity: Human
    • Application: Cytotoxicity assay, Function study
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For Research Use Only. Not For Clinical Use.


Creative Biolabs delivers high-quality anti-IL15R recombinant antibodies engineered for global customers. Our advanced platform generates antibodies with exceptional specificity, affinity, and stability. These antibodies exhibit diverse functionalities, including potent IL-15 signaling neutralization and precise subunit targeting, while minimizing off-target effects. In addition, we offer detailed validation data, including ELISA, FACS, WB, etc. We prioritize customer satisfaction, offering expert support and collaborating to tailor antibody solutions to your specific research needs, whether it involves cancer biology, immunotherapy development, or preclinical studies.

IL15R: A Potential Target for Cancer Therapy

The interleukin-15 receptor (IL-15R), a type I cytokine receptor, comprises the IL-2Rβ and γc subunits, alongside the unique IL-15Rα subunit, which exhibits structural homology to IL-2Rα. While initially recognized for its role in T-cell function, the IL-15/IL-15R signaling axis now emerges as a key regulator of diverse immune cell populations. By employing antibodies to precisely target IL-15 or IL-15R, researchers aim to achieve controlled modulation of immune responses, offering a promising avenue for the development of novel therapies for a range of diseases, including cancer, autoimmune disorders, and infectious diseases.

Table 1. Featured anti-IL15R recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
AGTO-G041D-mRNA Rat Anti-IL15R Antibody, mRNA Human Rat arthritis

Alternative Names

IL-15 receptor; Interleukin-15 receptor; CD215; interleukin-15 receptor subunit alpha; IL15RA.

Background

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.

Anti-IL15R rAb Products

Creative Biolabs stands at the forefront of antibody engineering, offering a diverse portfolio of recombinant anti-IL15R antibodies meticulously crafted to exhibit exceptional specificity and affinity. Our dedication to rigorous development ensures these antibodies are available in a variety of formats, catering to a spectrum of research needs and therapeutic applications. From fundamental investigations into immunology and cancer biology to the crucial stages of therapeutic development, our anti-IL15R antibodies empower researchers with cutting-edge tools. Based on our robust and innovative platform, Creative Biolabs is committed to advancing scientific understanding and accelerating the translation of research discoveries into impactful therapies.

Creative Quality Control

Creative Biolabs offers a comprehensive selection of recombinant anti-IL15R antibodies, each rigorously tested to ensure exceptional quality. Leveraging cutting-edge technology and the expertise of our skilled scientists, we meticulously design and develop antibodies with pinpoint accuracy to target the IL15R protein. Through a rigorous validation process, we guarantee superior specificity, high binding affinity, and optimal performance for a wide array of research applications.

Customer Reviews

Excellent
Za***y
Rat Anti-IL15R Antibody, mRNA (AGTO-G041D-mRNA)
I recently purchased the Rat Anti-IL15R Antibody, mRNA from Creative Biolabs for my ongoing research into T cell activation. The antibody arrived promptly and in excellent condition. I was particularly impressed with the high specificity and affinity of the antibody. It consistently and effectively bound to the target IL-15R protein in my experiments, yielding strong and reproducible results. The mRNA format was convenient for my research needs, allowing for efficient transfection and expression of the antibody within my cell lines.
11/May/2023
Excellent
Sh***o
Rat Anti-IL15R Antibody, mRNA (AGTO-G041D-mRNA)
The Rat Anti-IL15R Antibody, mRNA from Creative Biolabs is exceptional, and the technical support provided by the Creative Biolabs team was invaluable. Their expertise and responsiveness were instrumental in ensuring the successful implementation of the antibody in my research. I highly recommend this product to any researcher investigating IL-15R signaling pathways and its role in various biological processes. The high quality and reliability of this antibody have significantly streamlined my research and allowed me to achieve significant progress in my studies.
9/Oct/2023

rAb Production

Creative Biolabs ensures a reliable and consistent supply of high-quality anti-IL15R antibodies, manufactured utilizing advanced genetic engineering techniques.

Featured Anti-IL15R Recombinant Antibody Production PlatformsFig.1 Milligram-scale. (Creative Biolabs Original)
Fig.1 Milligram-scale anti-IL15R recombinant antibody production.

Fig.2 Gram-scale. (Creative Biolabs Original)Fig.2 Gram-scale anti-IL15R recombinant antibody production.

rAb Modalities

Creative Biolabs caters to the diverse needs of global researchers by offering a comprehensive selection of high-quality recombinant anti-IL15R antibodies in various formats.

Fig.3 IL15R antibody production and modalities. (Creative Biolabs Original)Fig.3 Full-length anti-IL15R recombinant antibody production and modalities.

IL15R-Targeted Drug Information

Table 2. Public drug targeting IL15R.

Company Research Phase Classification Condition
SOTIO Biotech (Originator)
SOTIO (SOTIO Biotech)
Phase I Cancer Immunotherapy
Fusion Proteins
Humanized Monoclonal Antibodies
IL-15
Immunocytokines
Polypeptides, from 41 AA
Cancer, solid tumor
IGM Biosciences (Originator) Phase I Antibodies
Cancer Immunotherapy
IL-15
Polypeptides, from 41 AA
Cancer, solid tumor
Hematologic-blood cancer
Cardion (Originator)
Roche
Preclinical Fusion Proteins
Polypeptides, from 41 AA
Crohn's disease
Rheumatoid arthritis
Transplant rejection
Xilio Therapeutics (Originator) Biological Testing Cancer Immunotherapy
IL-15
Polypeptides, from 41 AA
Recombinant proteins
Cancer

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

To learn more about our anti-IL15R recombinant antibody products or to place an order, please contact us today.

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