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IL27RA
Loading...Anti-IL27RA Products
- Anti-IL27RA Immunohistochemistry Kit (VS-0525-XY3519)
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- Species Reactivity: Human
- Target: IL27RA
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (NK-cells, T-cells, dendritic cells, B-cells, Langerhans cells, Kupffer cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR which interacts with the neuroprotective peptide humanin.
Molecular function
Receptor
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