+ Filter
Loading...
IL36A
Loading...Anti-IL36A Products
- AbPlus™ Anti-IL36A Magnetic Beads (VS-0724-YC1388) (VS-0724-YC1388)
-
- Target: IL36A
- Target Species: Human
- Application: IP, Protein Purification
Compare
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015]
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Not detected
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (JURKAT, MOLT-4, U-266/70)
Interaction
Interacts with TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion.
Molecular function
Cytokine
More Types Infomation