+ Filter
Loading...
IL37
Loading...Anti-IL37 Products
- Mouse Anti-IL37 Recombinant Antibody (clone 4C33) (NEUT-1394CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG2
- Application: Neut, WB
Compare
- Mouse Anti-IL37 Recombinant Antibody (clone CBL106) (NEUT-1393CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG2
- Application: Neut, WB
Compare
- Mouse Anti-IL37 Recombinant Antibody (clone CBL361) (NEUT-1395CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: Block
Compare
- Mouse Anti-IL37 Recombinant Antibody (HPAB-N0358-YC) (HPAB-N0358-YC)
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Block
Compare
- Mouse Anti-IL37 Recombinant Antibody; scFv Fragment (HPAB-N0358-YC-S(P)) (HPAB-N0358-YC-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, Block
Compare
- Mouse Anti-IL37 Recombinant Antibody; Fab Fragment (HPAB-N0358-YC-F(E)) (HPAB-N0358-YC-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, Block
Compare
View More Products
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18.
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enriched (Ionocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BJ hTERT+, PC-3, RT4)
Interaction
Interacts with SMAD3. Binds IL18R1, but not to IL1R1, with lower affinity than IL18, and does not seem to act as a receptor antagonist for IL18. Interacts with cargo receptor TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion (PubMed:32272059).
Molecular function
Cytokine
More Types Infomation