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For Research Use Only. Not For Clinical Use.
Disease related genes, Human disease related genes, Potential drug targets, Transporters
Intracellular, Membrane (different isoforms)
Group enriched (Sertoli cells, Cardiomyocytes, Smooth muscle cells, Astrocytes, Skeletal myocytes)
Not detected in immune cells
Cell line enriched (hTERT-RPE1)
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chain linked by a disulfide bond. Alpha-7 associates with beta-1. Interacts with COMP (By similarity). Interacts (via C-terminus intracellular tail region) with CIB1; the interaction is stabilized/increased in a calcium- and magnesium-dependent manner.
Integrin, Receptor