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ITGAD

Anti-ITGAD Products
- Human Anti-ITGAD Recombinant Antibody (HPAB-0252CQ) (HPAB-0252CQ)
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- Species Reactivity: Human, Rat
- Type: Human IgG1
- Application: ELISA, FC, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IF
- Human Anti-ITGAD Recombinant Antibody (HPAB-0014-SJF) (HPAB-0014-SJF)
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- Derivation: Humanized
- Species Reactivity: Human, rat
- Type: Humanized IgG4
- Application: FC, FuncS
- Human Anti-ITGAD Recombinant Antibody; scFv Fragment (HPAB-0252CQ-S(P)) (HPAB-0252CQ-S(P))
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- Species Reactivity: Human, Rat
- Type: Human scFv
- Application: ELISA, FC, FuncS
- Human Anti-ITGAD Recombinant Antibody; scFv Fragment (HPAB-0014-SJF-S(P)) (HPAB-0014-SJF-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, rat
- Type: Mouse scFv
- Application: FC, FuncS
- Human Anti-ITGAD Recombinant Antibody; Fab Fragment (HPAB-0014-SJF-F(E)) (HPAB-0014-SJF-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, rat
- Type: Humanized Fab
- Application: FC, FuncS
- Human Anti-ITGAD Recombinant Antibody; Fab Fragment (HPAB-0252CQ-F(E)) (HPAB-0252CQ-F(E))
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- Species Reactivity: Human, Rat
- Type: Human Fab
- Application: ELISA, FC, FuncS
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- Species Reactivity: Human, Rat
- Target: ITGAD
- Host Animal: Human
- Application: ELISA, FC, Cell-uptake
- Anti-Canine ITGAD Immunohistochemistry Kit (VS-0525-XY3637)
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- Species Reactivity: Canine
- Target: ITGAD
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants.
Protein class
CD markers
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Kupffer cells, T-cells, Macrophages, dendritic cells, Late spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Interaction
Heterodimer of an alpha and a beta subunit. Alpha-D associates with beta-2.
Molecular function
Integrin, Receptor
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